The role of red light therapy in the treatment of inflammation

Die Rolle der Rotlichttherapie bei der Behandlung von Entzündungen

Table of contents

What is inflammation and why does it occur?

Inflammation is a natural, complex immune response of the body to harmful stimuli such as infections, injuries, or toxins. Its goal is to neutralize the harmful substances and initiate the healing process. This mechanism sets in motion a cascade of events known as inflammatory signaling pathways.

When a cell is damaged, it releases cytokines and chemokines . These act like alarm molecules, attracting immune cells to rush to the site of inflammation. Once there, they release further substances that direct blood to the injury site, leading to swelling and redness.

Acute vs. Chronic Inflammation:

  • Acute inflammation : This occurs immediately after an injury or infection and can subside within a few hours to a few days. Acute inflammation is often painful, but it helps the body to cleanse the affected area and initiate healing.
  • Chronic inflammation : Inflammation becomes chronic when the body cannot break it down and it persists for weeks, months, or even years. Chronic inflammation is closely linked to diseases such as cardiovascular disease, diabetes, and certain cancers because it continuously damages surrounding tissue and disrupts normal cell function.

Effects of inflammation on the body and specific diseases

Chronic inflammation can affect many of the body's systems and cause various diseases. Here are some detailed examples:

  • Arthritis and joint diseases : Arthritis encompasses a group of diseases associated with inflammation in the joints. In rheumatoid arthritis, in particular, the immune system attacks the body's own tissue, leading to persistent inflammation. This attack damages cartilage tissue and can cause irreversible deformities and functional limitations.
  • Cardiovascular diseases : Chronic inflammation of the artery walls plays a central role in the development of arteriosclerosis. Inflammatory processes lead to the formation of plaques that narrow the arteries and restrict blood flow. If a plaque becomes unstable and ruptures, this can lead to a heart attack or stroke.
  • Type 2 diabetes : High blood sugar levels can promote chronic inflammation, which impairs the function of insulin production and utilization. Inflammatory mediators disrupt insulin sensitivity and contribute to the development of insulin resistance.
  • Neurodegenerative diseases : There is evidence that chronic inflammation in the brain plays a role in diseases such as Alzheimer's and Parkinson's. Microglia, the brain's immune cells, release inflammatory molecules that can damage nerve cells and lead to neuronal degeneration.

What is red light therapy and how does it work?

Red light therapy is a form of photobiomodulation that uses light with specific wavelengths (usually between 600 nm and 850 nm) to penetrate deep into the skin and underlying tissue. Red light (approx. 630–660 nm) and infrared light (approx. 810–850 nm) penetrate deeply enough to stimulate cellular processes at the molecular level, particularly the mitochondria – the “powerhouses” of our cells.

The wavelengths of red light activate cytochrome c oxidase , an enzyme in the mitochondria that stimulates the production of ATP (adenosine triphosphate). ATP is the energy source that powers all cellular functions. Increased ATP production supports cell regeneration and can boost anti-inflammatory processes.

Other mechanisms of red light therapy:

  • Antioxidant effect : Red light can promote the production of nitric oxide, which improves blood circulation and reduces oxidative stress.
  • Reduction of pro-inflammatory cytokines : Studies show that red light can lower the concentration of cytokines such as TNF-alpha and IL-6, which are often elevated in chronic inflammation.

How red light therapy specifically helps with inflammation

Red light therapy works on various levels to alleviate inflammation and its symptoms. Here are some specific effects:

  • Reduction of inflammatory processes : By inhibiting pro-inflammatory cytokines and stimulating antioxidant mechanisms, red light therapy can directly influence the inflammatory process. This is particularly beneficial in chronic inflammations, which are difficult to treat and often cause pain.
  • Improved cell function and tissue repair : Increased ATP production accelerates cell division and the production of proteins needed to repair damaged tissue. Studies have shown that injuries such as muscle tears or skin wounds heal faster with red light irradiation.
  • Pain relief through influencing pain receptors : Red light can soothe pain receptors by promoting the release of pain-relieving neurotransmitters. At the same time, it stimulates blood circulation, which supports the removal of inflammatory mediators.

Practical tips for using red light therapy for inflammation

For optimal results, the correct application of red light therapy is crucial:

  • Session duration and frequency : For treating inflammation, it is recommended to use the light for 10–20 minutes per session. The frequency should be at least three times per week, and daily in cases of severe inflammation. Long-term use often shows lasting improvement.
  • Distance to the light source : A distance of 15 to 30 cm is ideal. This allows the light to penetrate deep enough into the tissue without overheating the skin. Infrared light penetrates deeper and is therefore particularly suitable for joints and muscles.
  • Combination with other methods : The effects of red light therapy can be enhanced by measures such as gentle exercise and an anti-inflammatory diet. These factors can further promote the reduction of inflammation and support the healing process.

Closing remarks

In summary, red light therapy offers a natural and effective way to reduce inflammation in the body, alleviate pain, and accelerate the healing of damaged tissue. Red light can be a particularly valuable addition to treatment for chronic inflammation, which places a long-term burden on the body.

Do you suffer from chronic or frequently recurring inflammation? Try red light therapy and experience relief. With us, you're also protected with a 30-day trial period.


About the author

Yike Pan

Yike Pan is the founder of heilys®, an engineer, and a light researcher. With over 20 years of experience in electrical engineering, architectural lighting, and research at Eindhoven University of Technology, he is now dedicated to a clear mission: bringing healthy, bioactive light into everyday life—precisely, effectively, and scientifically.


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